British Pharmacopoeia Chemical reference substances (BPCRS)

These Primary standards are established using absolute methods and the declared content figures are determined without comparing to another substance. You should use BPCRS to perform the tests in the British Pharmacopoeia (BP) or BP (Veterinary). Do not eat BPCRS or feed them to animals – you should only use BPCRS for chemical analysis. They are not suitable for any other use.

30/06/2025

Dear valued customer,

We are writing to let you know that, due to an electrical fault, our freezers in which some BPCRS vial stock was stored switched off for a short period and the storage temperature may have been compromised over the weekend of 21st/22nd June. This was detected promptly and rectified, but as a precaution we have removed all affected items from sale and are conducting thorough testing to verify their stability and usability.

Consequently, you may notice in the short term that a higher number of products than usual are showing as “out of stock”. This process is necessary to ensure that only products that meet our quality standards are shipped to you.

We sincerely apologise for any inconvenience and appreciate your patience and understanding, and would like to reassure you that;

· None of the affected vials have been shipped to customers.

· All affected vials have been quarantined.

· We are urgently reviewing the material stability data and carrying out testing to determine if the material has been affected.

· We have additional bulk supplies of the materials which have not been affected and we can produce more vials from these bulks.

Products will be brought back into stock as soon as we can confirm they have not been affected. As we assess the products and gather more data we will be able to update with estimated timeframes in due course. As soon as we have further information we will update this page.

Update 18/07/25

We are pleased to update that over the last three weeks we have made the following products available for sale, following their temporary withdrawal resulting from an electrical fault affecting freezers.

This follows a detailed quality assessment of some of our vialled stock and re-vialing product from our reserved bulk supplies:

CAT 26 (azathioprine), CAT 108 (dexamethasone sodium phosphate), CAT 341 (3,5,6-trichloro-2-hydroxybenzoic acid), CAT 362 (naftidrofuryl oxalate), CAT 400 (rifampicin N-oxide), CAT 640 (N,N'-bis(2,4-xylyl)formamidine), CAT 641 (N-methyl-N'-(2,4-xylyl)formamidine), CAT 654 (famotidine impurity C), CAT 704 (salbutamol ketone impurity), CAT 781 (erythromycin), CAT 789 (demeclocycline hydrochloride), CAT 791 (delta-3-cefaclor), CAT 876 (tamsulosin hydrochloride), CAT 894 (budesonide impurity standard), CAT 1027 (piperacillin), CAT 1030 (pravastatin impurity A), CAT 1106 (nicorandil amide), CAT 1150 (colchicine), CAT 1165 (palmatine chloride), CAT 1167 (vecuronium bromide), CAT 1193 (quinapril hydrochloride).

We are continuing to review all remaining affected products, with further products expected to be made available next week, and most affected items expected to be made available by the end of July.

We would like to thank you again for your patience while we have worked to resolve this matter.

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  • Search result 1

    Category Number 745
    Pack size 25 mg
    Substance name sumatriptan impurity standard
    Declared content Not applicable
    Current batch 2791
    E-mail to order:  bpcrs@mhra.gov.uk
  • Search result 2

    Category Number 950
    Pack size 100 mg
    Substance name sumatriptan succinate
    Declared content
    99.0% of C18H27N3O6S
    Current batch 3300
    Out of Stock
  • Search result 3

    Category Number 1225
    Pack size 100 mg
    Substance name tamoxifen citrate
    Declared content
    65.8% of C26H29NO
    Current batch 4097
    QTY (Max 25)
  • Search result 4

    Category Number 876
    Pack size 100 mg
    Substance name tamsulosin hydrochloride
    Declared content
    99.9 % of C20H28N2O5S,HCl
    Current batch 4474
    QTY (Max 25)
  • Search result 5

    Category Number 877
    Pack size 25 mg
    Substance name tamsulosin hydrochloride impurity standard
    Declared content Not applicable
    Current batch 4531
    Out of Stock
  • Search result 6

    Category Number 1202
    Pack size 100 mg
    Substance name telmisartan
    Declared content
    99.4% of C33H30N4O2
    Current batch 3971
    QTY (Max 25)
  • Search result 7

    Category Number 455
    Pack size 100 mg
    Substance name temazepam
    Declared content
    100.0% of C16H13ClN2O2
    Current batch 4166
    QTY (Max 5)
  • Search result 8

    Category Number 1246
    Pack size 100 mg
    Substance name temozolomide
    Declared content
    99.5% of C6H6N6O2
    Current batch 4247
    QTY (Max 2)
  • Search result 9

    Category Number 708
    Pack size 100 mg
    Substance name tenoxicam
    Declared content
    99.6% of C13H11N3O4S2
    Current batch 4260
    QTY (Max 25)
  • Search result 10

    Category Number 709
    Pack size 25 mg
    Substance name tenoxicam degradation impurity standard
    Declared content Not applicable
    Current batch 4438
    QTY (Max 25)
  • Search result 11

    Category Number 1159
    Pack size 100 mg
    Substance name terbinafine hydrochloride
    Declared content
    99.7% of C21H26CIN
    88.6% of C21H25N
    Current batch 3801
    QTY (Max 25)
  • Search result 12

    Category Number 1045
    Pack size 15 mg
    Substance name terbutaline impurity C
    Declared content Not applicable
    Current batch 3253
    QTY (Max 25)
  • Search result 13

    Category Number 1317
    Pack size 100mg
    Substance name terbutaline impurity standard
    Declared content Not applicable
    Current batch 4877
    QTY (Max 25)
  • Search result 14

    Category Number 318
    Pack size 100 mg
    Substance name terbutaline sulfate
    Declared content
    99.9% of (C12H19NO3)2,H2SO4
    Current batch 3165
    QTY (Max 25)
  • Search result 15

    Category Number 650
    Pack size 100 mg
    Substance name terfenadine
    Declared content
    99.8% of C32H41NO2
    Current batch 2210
    QTY (Max 25)
  • Search result 16

    Category Number 1076
    Pack size 25 mg
    Substance name testosterone
    Declared content Not applicable
    Current batch 3469
    QTY (Max 25)
  • Search result 17

    Category Number 319
    Pack size 100 mg
    Substance name testosterone decanoate
    Declared content Not applicable
    Current batch 3159
    QTY (Max 25)
  • Search result 18

    Category Number 728
    Pack size 100 mg
    Substance name testosterone enantate
    Declared content
    96.7 % of C26H40O3
    Current batch 4412
    Discontinued
  • Search result 19

    Category Number 321
    Pack size 100 mg
    Substance name testosterone isocaproate
    Declared content Not applicable
    Current batch 3162
    QTY (Max 25)
  • Search result 20

    Category Number 322
    Pack size 100 mg
    Substance name testosterone phenylpropionate
    Declared content
    99.9% of C28H36O3
    Current batch 3160
    Discontinued