British Pharmacopoeia Chemical reference substances (BPCRS)

These Primary standards are established using absolute methods and the declared content figures are determined without comparing to another substance. You should use BPCRS to perform the tests in the British Pharmacopoeia (BP) or BP (Veterinary). Do not eat BPCRS or feed them to animals – you should only use BPCRS for chemical analysis. They are not suitable for any other use.

30/06/2025

Dear valued customer,

We are writing to let you know that, due to an electrical fault, our freezers in which some BPCRS vial stock was stored switched off for a short period and the storage temperature may have been compromised over the weekend of 21st/22nd June. This was detected promptly and rectified, but as a precaution we have removed all affected items from sale and are conducting thorough testing to verify their stability and usability.

Consequently, you may notice in the short term that a higher number of products than usual are showing as “out of stock”. This process is necessary to ensure that only products that meet our quality standards are shipped to you.

We sincerely apologise for any inconvenience and appreciate your patience and understanding, and would like to reassure you that;

· None of the affected vials have been shipped to customers.

· All affected vials have been quarantined.

· We are urgently reviewing the material stability data and carrying out testing to determine if the material has been affected.

· We have additional bulk supplies of the materials which have not been affected and we can produce more vials from these bulks.

Products will be brought back into stock as soon as we can confirm they have not been affected. As we assess the products and gather more data we will be able to update with estimated timeframes in due course. As soon as we have further information we will update this page.

Update 18/07/25

We are pleased to update that over the last three weeks we have made the following products available for sale, following their temporary withdrawal resulting from an electrical fault affecting freezers.

This follows a detailed quality assessment of some of our vialled stock and re-vialing product from our reserved bulk supplies:

CAT 26 (azathioprine), CAT 108 (dexamethasone sodium phosphate), CAT 341 (3,5,6-trichloro-2-hydroxybenzoic acid), CAT 362 (naftidrofuryl oxalate), CAT 400 (rifampicin N-oxide), CAT 640 (N,N'-bis(2,4-xylyl)formamidine), CAT 641 (N-methyl-N'-(2,4-xylyl)formamidine), CAT 654 (famotidine impurity C), CAT 704 (salbutamol ketone impurity), CAT 781 (erythromycin), CAT 789 (demeclocycline hydrochloride), CAT 791 (delta-3-cefaclor), CAT 876 (tamsulosin hydrochloride), CAT 894 (budesonide impurity standard), CAT 1027 (piperacillin), CAT 1030 (pravastatin impurity A), CAT 1106 (nicorandil amide), CAT 1150 (colchicine), CAT 1165 (palmatine chloride), CAT 1167 (vecuronium bromide), CAT 1193 (quinapril hydrochloride).

We are continuing to review all remaining affected products, with further products expected to be made available next week, and most affected items expected to be made available by the end of July.

We would like to thank you again for your patience while we have worked to resolve this matter.

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  • Search result 1

    Category Number 458
    Pack size 100 mg
    Substance name pyridoxine hydrochloride
    Declared content
    100.0% of C8H11NO3,HCl
    Current batch 4092
    Out of Stock
  • Search result 2

    Category Number 1227
    Pack size 100 mg
    Substance name pyrimethamine
    Declared content
    99.5% of C12H13CIN4
    Current batch 4113
    QTY (Max 25)
  • Search result 3

    Category Number 1215
    Pack size 100 mg
    Substance name quetiapine fumarate
    Declared content
    99.7 % of C46H54N6O8S2 for HPLC 100.0 % of C46H54N6O8S2 for UV
    Current batch 4042
    QTY (Max 25)
  • Search result 4

    Category Number 1217
    Pack size 25 mg
    Substance name quetiapine impurity G
    Declared content Not applicable
    Current batch 4070
    QTY (Max 25)
  • Search result 5

    Category Number 1216
    Pack size 25 mg
    Substance name quetiapine impurity I
    Declared content Not applicable
    Current batch 4102
    QTY (Max 25)
  • Search result 6

    Category Number 1193
    Pack size 100 mg
    Substance name quinapril hydrochloride
    Declared content
    99.3% of C25H30N2O5, HCl
    Current batch 3930
    QTY (Max 25)
  • Search result 7

    Category Number 863
    Pack size 300 mg
    Substance name quinidine sulfate
    Declared content Not applicable
    Current batch 3876
    Out of Stock
  • Search result 8

    Category Number 862
    Pack size 300 mg
    Substance name quinine sulfate
    Declared content
    96.8% of (C20H24N2O2)2,H2SO4,2H2O
    Current batch 4695
    QTY (Max 25)
  • Search result 9

    Category Number 751
    Pack size 100 mg
    Substance name ramipril
    Declared content
    99.9% of C23H32N2O5
    Current batch 3446
    QTY (Max 25)
  • Search result 10

    Category Number 754
    Pack size 25 mg
    Substance name ramipril impurity K
    Declared content Not applicable
    Current batch 3555
    QTY (Max 25)
  • Search result 11

    Category Number 471
    Pack size 100 mg
    Substance name ranitidine hydrochloride
    Declared content
    89.3% of C13H22N4O3S
    Current batch 3987
    QTY (Max 25)
  • Search result 12

    Category Number 1240
    Pack size 100 mg
    Substance name repaglinide
    Declared content
    99.9 % of C27H36N2O4
    Current batch 4172
    QTY (Max 25)
  • Search result 13

    Category Number 1252
    Pack size 2 mL
    Substance name repaglinide impurity standard solution
    Declared content Not applicable
    Current batch 4305
    QTY (Max 10)
  • Search result 14

    Category Number 593
    Pack size 100 mg
    Substance name ribavirin
    Declared content
    99.9% of C8H12N4O5
    Current batch 1980
    QTY (Max 25)
  • Search result 15

    Category Number 592
    Pack size 50 mg
    Substance name ribavirin impurity standard
    Declared content Not applicable
    Current batch 2015
    QTY (Max 2)
  • Search result 16

    Category Number 459
    Pack size 50 mg
    Substance name riboflavin sodium phosphate
    Declared content Not applicable
    Current batch 3382
    QTY (Max 25)
  • Search result 17

    Category Number 400
    Pack size 25 mg
    Substance name rifampicin N-oxide
    Declared content Not applicable
    Current batch 4025
    QTY (Max 25)
  • Search result 18

    Category Number 1241
    Pack size 100 mg
    Substance name risedronate sodium 2.5-hydrate
    Declared content
    86.2% of C7H10NNaO7P2
    Current batch 4157
    Out of Stock
  • Search result 19

    Category Number 1137
    Pack size 100 mg
    Substance name risperidone
    Declared content
    100.0% of C23H27FN4O2
    Current batch 3568
    QTY (Max 25)
  • Search result 20

    Category Number 1158
    Pack size 25 mg
    Substance name risperidone impurity standard
    Declared content Not applicable
    Current batch 4504
    QTY (Max 25)