British Pharmacopoeia Chemical reference substances (BPCRS)

These Primary standards are established using absolute methods and the declared content figures are determined without comparing to another substance. You should use BPCRS to perform the tests in the British Pharmacopoeia (BP) or BP (Veterinary). Do not eat BPCRS or feed them to animals – you should only use BPCRS for chemical analysis. They are not suitable for any other use.

30/06/2025

Dear valued customer,

We are writing to let you know that, due to an electrical fault, our freezers in which some BPCRS vial stock was stored switched off for a short period and the storage temperature may have been compromised over the weekend of 21st/22nd June. This was detected promptly and rectified, but as a precaution we have removed all affected items from sale and are conducting thorough testing to verify their stability and usability.

Consequently, you may notice in the short term that a higher number of products than usual are showing as “out of stock”. This process is necessary to ensure that only products that meet our quality standards are shipped to you.

We sincerely apologise for any inconvenience and appreciate your patience and understanding, and would like to reassure you that;

· None of the affected vials have been shipped to customers.

· All affected vials have been quarantined.

· We are urgently reviewing the material stability data and carrying out testing to determine if the material has been affected.

· We have additional bulk supplies of the materials which have not been affected and we can produce more vials from these bulks.

Products will be brought back into stock as soon as we can confirm they have not been affected. As we assess the products and gather more data we will be able to update with estimated timeframes in due course. As soon as we have further information we will update this page.

Update 18/07/25

We are pleased to update that over the last three weeks we have made the following products available for sale, following their temporary withdrawal resulting from an electrical fault affecting freezers.

This follows a detailed quality assessment of some of our vialled stock and re-vialing product from our reserved bulk supplies:

CAT 26 (azathioprine), CAT 108 (dexamethasone sodium phosphate), CAT 341 (3,5,6-trichloro-2-hydroxybenzoic acid), CAT 362 (naftidrofuryl oxalate), CAT 400 (rifampicin N-oxide), CAT 640 (N,N'-bis(2,4-xylyl)formamidine), CAT 641 (N-methyl-N'-(2,4-xylyl)formamidine), CAT 654 (famotidine impurity C), CAT 704 (salbutamol ketone impurity), CAT 781 (erythromycin), CAT 789 (demeclocycline hydrochloride), CAT 791 (delta-3-cefaclor), CAT 876 (tamsulosin hydrochloride), CAT 894 (budesonide impurity standard), CAT 1027 (piperacillin), CAT 1030 (pravastatin impurity A), CAT 1106 (nicorandil amide), CAT 1150 (colchicine), CAT 1165 (palmatine chloride), CAT 1167 (vecuronium bromide), CAT 1193 (quinapril hydrochloride).

We are continuing to review all remaining affected products, with further products expected to be made available next week, and most affected items expected to be made available by the end of July.

We would like to thank you again for your patience while we have worked to resolve this matter.

951 items
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  • Search result 1

    Category Number 161
    Pack size 50 mg
    Substance name fluocortolone hexanoate
    Declared content
    98.5% of C28H39FO5
    Current batch 2111
    Discontinued
  • Search result 2

    Category Number 162
    Pack size 50 mg
    Substance name fluocortolone pivalate
    Declared content
    98.0% of C27H37FO5
    Current batch 1610
    Discontinued
  • Search result 3

    Category Number 573
    Pack size 100 mg
    Substance name fluorometholone
    Declared content
    99.8% of C22H29FO4
    Current batch 3009
    QTY (Max 25)
  • Search result 4

    Category Number 995
    Pack size 40 mg
    Substance name fluorouracil
    Declared content Not applicable
    Current batch 3246
    QTY (Max 25)
  • Search result 5

    Category Number 797
    Pack size 250 mg
    Substance name fluoxetine hydrochloride
    Declared content
    97.6 % of C17H18F3NO,HCl
    Current batch 4832
    QTY (Max 25)
  • Search result 6

    Category Number 164
    Pack size 50 mg
    Substance name fluoxymesterone
    Declared content Not applicable
    Current batch 2995
    QTY (Max 25)
  • Search result 7

    Category Number 554
    Pack size 100 mg
    Substance name flupentixol decanoate dihydrochloride
    Declared content
    99.5% of C33H43F3N2O2S, 2HCl
    Current batch 3084
    Out of Stock
  • Search result 8

    Category Number 1132
    Pack size 100 mg
    Substance name flupentixol dihydrochloride
    Declared content
    83.2 % of C23H25F3N2OS
    Current batch 4727
    QTY (Max 25)
  • Search result 9

    Category Number 167
    Pack size 100 mg
    Substance name fluphenazine hydrochloride
    Declared content
    99.2% of C22H26F3N3OS, 2HCl
    Current batch 3749
    QTY (Max 25)
  • Search result 10

    Category Number 574
    Pack size 100 mg
    Substance name flurbiprofen sodium
    Declared content
    99.6% of C15H13FO2
    108.5% of C15H12FNaO2
    123.2% of C15H12FNaO2, 2H2O
    Current batch 4060
    QTY (Max 1)
  • Search result 11

    Category Number 587
    Pack size 100 mg
    Substance name fluticasone propionate
    Declared content
    99.7% of C25H31F3O5S
    Current batch 4030
    QTY (Max 25)
  • Search result 12

    Category Number 588
    Pack size 25 mg
    Substance name fluticasone S-methyl impurity
    Declared content Not applicable
    Current batch 3322
    Discontinued
  • Search result 13

    Category Number 1189
    Pack size 25 mg
    Substance name fluvastatin impurity F
    Declared content
    See leaflet provided with the BPCRS
    Current batch 4589
    Out of Stock
  • Search result 14

    Category Number 1163
    Pack size 100 mg
    Substance name fluvastatin sodium
    Declared content
    97.4% of C24H25NNaO4
    Current batch 4581
    Out of Stock
  • Search result 15

    Category Number 1190
    Pack size 25 mg
    Substance name fluvoxamine impurity D
    Declared content Not applicable
    Current batch 3912
    QTY (Max 25)
  • Search result 16

    Category Number 600
    Pack size 100 mg
    Substance name fluvoxamine maleate
    Declared content
    99.6% of C15H21F3N2O2,C4H4O4
    Current batch 2680
    QTY (Max 1)
  • Search result 17

    Category Number 671
    Pack size 100 mg
    Substance name fluvoxamine maleate impurity standard
    Declared content Not applicable
    Current batch 3099
    QTY (Max 25)
  • Search result 18

    Category Number 937
    Pack size 150 mg
    Substance name folic acid
    Declared content
    91.2% of C19H19N7O6
    Current batch 3282
    QTY (Max 25)
  • Search result 19

    Category Number 639
    Pack size 25 mg
    Substance name form-2',4'-xylidide
    Declared content Not applicable
    Current batch 3426
    Out of Stock
  • Search result 20

    Category Number 1129
    Pack size 25 mg
    Substance name formononetin
    Declared content Not applicable
    Current batch 3668
    E-mail to order:  bpcrs@mhra.gov.uk