British Pharmacopoeia Chemical reference substances (BPCRS)

These Primary standards are established using absolute methods and the declared content figures are determined without comparing to another substance. You should use BPCRS to perform the tests in the British Pharmacopoeia (BP) or BP (Veterinary). Do not eat BPCRS or feed them to animals – you should only use BPCRS for chemical analysis. They are not suitable for any other use.

30/06/2025

Dear valued customer,

We are writing to let you know that, due to an electrical fault, our freezers in which some BPCRS vial stock was stored switched off for a short period and the storage temperature may have been compromised over the weekend of 21st/22nd June. This was detected promptly and rectified, but as a precaution we have removed all affected items from sale and are conducting thorough testing to verify their stability and usability.

Consequently, you may notice in the short term that a higher number of products than usual are showing as “out of stock”. This process is necessary to ensure that only products that meet our quality standards are shipped to you.

We sincerely apologise for any inconvenience and appreciate your patience and understanding, and would like to reassure you that;

· None of the affected vials have been shipped to customers.

· All affected vials have been quarantined.

· We are urgently reviewing the material stability data and carrying out testing to determine if the material has been affected.

· We have additional bulk supplies of the materials which have not been affected and we can produce more vials from these bulks.

Products will be brought back into stock as soon as we can confirm they have not been affected. As we assess the products and gather more data we will be able to update with estimated timeframes in due course. As soon as we have further information we will update this page.

Update 18/07/25

We are pleased to update that over the last three weeks we have made the following products available for sale, following their temporary withdrawal resulting from an electrical fault affecting freezers.

This follows a detailed quality assessment of some of our vialled stock and re-vialing product from our reserved bulk supplies:

CAT 26 (azathioprine), CAT 108 (dexamethasone sodium phosphate), CAT 341 (3,5,6-trichloro-2-hydroxybenzoic acid), CAT 362 (naftidrofuryl oxalate), CAT 400 (rifampicin N-oxide), CAT 640 (N,N'-bis(2,4-xylyl)formamidine), CAT 641 (N-methyl-N'-(2,4-xylyl)formamidine), CAT 654 (famotidine impurity C), CAT 704 (salbutamol ketone impurity), CAT 781 (erythromycin), CAT 789 (demeclocycline hydrochloride), CAT 791 (delta-3-cefaclor), CAT 876 (tamsulosin hydrochloride), CAT 894 (budesonide impurity standard), CAT 1027 (piperacillin), CAT 1030 (pravastatin impurity A), CAT 1106 (nicorandil amide), CAT 1150 (colchicine), CAT 1165 (palmatine chloride), CAT 1167 (vecuronium bromide), CAT 1193 (quinapril hydrochloride).

We are continuing to review all remaining affected products, with further products expected to be made available next week, and most affected items expected to be made available by the end of July.

We would like to thank you again for your patience while we have worked to resolve this matter.

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  • Search result 1

    Category Number 145
    Pack size 100 mg
    Substance name ethopabate
    Declared content
    98.8% of C12H15NO4
    Current batch 2611
    QTY (Max 25)
  • Search result 2

    Category Number 146
    Pack size 200 mg
    Substance name ethosuximide
    Declared content
    100.0% of C7H11NO2
    Current batch 3456
    QTY (Max 25)
  • Search result 3

    Category Number 149
    Pack size 25 mg
    Substance name ethyl meclofenamate
    Declared content Not applicable
    Current batch 1265
    Discontinued
  • Search result 4

    Category Number 150
    Pack size 1
    Declared content Not applicable
    Current batch
    Discontinued
  • Search result 5

    Category Number 529
    Pack size 150 mg
    Substance name etodolac
    Declared content
    99.8 % of C17H21NO3
    Current batch 4282
    QTY (Max 25)
  • Search result 6

    Category Number 541
    Pack size 10 mg
    Substance name etodolac 1-methyl analogue
    Declared content Not applicable
    Current batch 4076
    QTY (Max 25)
  • Search result 7

    Category Number 542
    Pack size 10 mg
    Substance name etodolac 8-methyl analogue
    Declared content Not applicable
    Current batch 3247
    QTY (Max 25)
  • Search result 8

    Category Number 533
    Pack size 10 mg
    Substance name etodolac acid dimer
    Declared content Not applicable
    Current batch 3229
    Out of Stock
  • Search result 9

    Category Number 885
    Pack size 150 mg
    Substance name etoposide
    Declared content
    96.2 % of C29H32O13
    Current batch 4829
    Out of Stock
  • Search result 10

    Category Number 1131
    Pack size 100 mg
    Substance name etynodiol diacetate
    Declared content
    97.8% of C24H32O4
    Current batch 4051
    E-mail to order:  bpcrs@mhra.gov.uk
  • Search result 11

    Category Number 653
    Pack size 100 mg
    Substance name famotidine
    Declared content
    99.7% of C8H15N7O2S3
    Current batch 3088
    QTY (Max 25)
  • Search result 12

    Category Number 655
    Pack size 25 mg
    Substance name famotidine degradation impurity 1
    Declared content Not applicable
    Current batch 3936
    Out of Stock
  • Search result 13

    Category Number 656
    Pack size 25 mg
    Substance name famotidine degradation impurity 2
    Declared content Not applicable
    Current batch 3068
    Discontinued
  • Search result 14

    Category Number 654
    Pack size 25 mg
    Substance name famotidine impurity C
    Declared content Not applicable
    Current batch 3799
    Out of Stock
  • Search result 15

    Category Number 620
    Pack size 100 mg
    Substance name felbinac
    Declared content
    100.0% of C14H12O2
    Current batch 4395
    QTY (Max 25)
  • Search result 16

    Category Number 777
    Pack size 100 mg
    Substance name felodipine
    Declared content
    99.8% of C18H19Cl2NO4
    Current batch 2825
    QTY (Max 25)
  • Search result 17

    Category Number 758
    Pack size 20 mg
    Substance name felodipine impurity standard
    Declared content Not applicable
    Current batch 2856
    QTY (Max 25)
  • Search result 18

    Category Number 692
    Pack size 100 mg
    Substance name fenbendazole
    Declared content
    99.6% of C15H13N3O2S
    Current batch 3808
    Out of Stock
  • Search result 19

    Category Number 693
    Pack size 25 mg
    Substance name fenbendazole impurity 1
    Declared content Not applicable
    Current batch 4621
    QTY (Max 25)
  • Search result 20

    Category Number 354
    Pack size 100 mg
    Substance name fenbufen
    Declared content
    99.6% of C16H14O3
    Current batch 1871
    QTY (Max 25)